Small Molecules & Supplements

7 compounds tracked in this category with source-backed claims and regulatory status.

SMALL MOLECULE

5-Amino-1MQ (5-amino-1-methylquinoline) is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in cell...

3 claims · 2 sources · Regulatory watch

SENOLYTIC COMPOUND

Fisetin is a naturally occurring flavonoid (3,3',4',7-tetrahydroxyflavone) found in fruits and vegetables (strawberries, apples, onions) tha...

3 claims · 3 sources · Evidence review

LONGEVITY SMALL MOLECULE

Metformin is an FDA-approved biguanide antidiabetic (marketed as Glucophage and generics) used as first-line therapy for Type 2 diabetes. It...

4 claims · 6 sources · Evidence review

SMALL MOLECULE

Methylene blue (methylthioninium chloride) is an FDA-approved medication (trade names Provayblue, Proveblue) for the treatment of methemoglo...

3 claims · 4 sources · Regulatory watch

LONGEVITY SUPPLEMENT

NAD+ (nicotinamide adenine dinucleotide) is an essential cellular coenzyme whose levels decline with age. Two precursors — nicotinamide ribo...

4 claims · 8 sources · Regulatory watch

LONGEVITY SMALL MOLECULE

Rapamycin (sirolimus) is an FDA-approved mTOR inhibitor (marketed as Rapamune) used to prevent organ transplant rejection and to treat lymph...

4 claims · 8 sources · Evidence review

LONGEVITY SUPPLEMENT

Spermidine is a naturally occurring polyamine (1-(3-aminopropyl)butane-1,4-diamine) found in wheat germ, aged cheese, mushrooms, and soy pro...

3 claims · 5 sources · Evidence review